Francois D'Hooge Selected Research

pyrrolo(2,1-c)(1,4)benzodiazepine

1/2020	TR1801-ADC: a highly potent cMet antibody-drug conjugate with high activity in patient-derived xenograft models of solid tumors.
10/2018	Antitumor Activity of MEDI3726 (ADCT-401), a Pyrrolobenzodiazepine Antibody-Drug Conjugate Targeting PSMA, in Preclinical Models of Prostate Cancer.
11/2016	ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody-Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies.

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Francois D'Hooge Research Topics

Disease

8	Neoplasms (Cancer) 01/2020 - 11/2015
2	Lymphoma (Lymphomas) 01/2018 - 11/2016
1	Stomach Neoplasms (Stomach Cancer) 01/2020
1	Infections 01/2019
1	African Trypanosomiasis (Nagana) 01/2019
1	Prostatic Neoplasms (Prostate Cancer) 10/2018
1	Leukemia 01/2018
1	Carcinoma (Carcinomatosis) 01/2017
1	Hematologic Neoplasms (Hematological Malignancy) 11/2016

Drug/Important Bio-Agent (IBA)

7	Immunoconjugates (Immunoconjugate)IBA 01/2020 - 11/2015
3	pyrrolo(2,1-c)(1,4)benzodiazepineIBA 01/2020 - 11/2016
3	DNA (Deoxyribonucleic Acid)IBA 10/2018 - 11/2016
2	AntigensIBA 10/2018 - 01/2017
1	ProdrugsIBA 10/2019
1	GlucuronidaseIBA 10/2019
1	Pharmaceutical PreparationsIBA 10/2019
1	HaptoglobinsIBA 01/2019
1	MEDI3726IBA 10/2018
1	glutamate carboxypeptidaseIBA 10/2018
1	Histones (Histone)IBA 10/2018
1	Tubulin ModulatorsIBA 01/2018
1	loncastuximab tesirineIBA 01/2018
1	Immunoglobulins (Immunoglobulin)IBA 01/2018
1	Membrane Glycoproteins (Membrane Glycoprotein)IBA 01/2018
1	CD19 AntigensIBA 01/2018
1	Trastuzumab (Herceptin)FDA Link 01/2017
1	Cytotoxins (Cytolysins)IBA 01/2017
1	MEDI0641IBA 01/2017
1	Antineoplastic Agents (Antineoplastics)IBA 11/2015

Therapy/Procedure

1	Castration 10/2018
1	Drug Therapy (Chemotherapy) 11/2015